Vascular effects of RWJ-676070, a selective combined V1a/V2 vasopressin receptor antagonist

Clin Pharmacol Ther. 2009 Feb;85(2):145-8. doi: 10.1038/clpt.2008.217. Epub 2008 Nov 5.

Authors

L Coltamai¹, M Bucher, M P Maillard, U Shukla, N Bohidar, L Haskell, K Bertelsen, M Fedgchin, B Vogt, M Burnier

Affiliation

¹ Department of Medicine, Division of Nephrology and Hypertension, Central University Hospital of Vaud, Lausanne, Switzerland.

PMID: 18987622
DOI: 10.1038/clpt.2008.217

No abstract available

Publication types

Comparative Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Antidiuretic Hormone Receptor Antagonists*
Benzazepines / pharmacology*
Cross-Over Studies
Dose-Response Relationship, Drug
Double-Blind Method
Humans
Male
Receptors, Vasopressin / physiology
Regional Blood Flow / drug effects*
Regional Blood Flow / physiology
Skin / blood supply*
Skin / drug effects*
Spiro Compounds / pharmacology*
Young Adult

Substances

Antidiuretic Hormone Receptor Antagonists
Benzazepines
RWJ-676070
Receptors, Vasopressin
Spiro Compounds