Novel human rhinoviruses and exacerbation of asthma in children

Emerg Infect Dis. 2008 Nov;14(11):1793-6. doi: 10.3201/eid1411.080386.

Abstract

To determine links between human rhinoviruses (HRV) and asthma, we used data from a case-control study, March 2003-February 2004, among children with asthma. Molecular characterization identified several likely new HRVs and showed that association with asthma exacerbations was largely driven by HRV-A and a phylogenetically distinct clade of 8 strains, genogroup C.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Asthma / epidemiology
  • Asthma / pathology*
  • Asthma / virology*
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Disease Progression
  • Georgia
  • Humans
  • Phylogeny
  • Picornaviridae Infections / complications*
  • Rhinovirus / classification*
  • Rhinovirus / genetics
  • Rhinovirus / isolation & purification
  • Urban Population
  • Viral Proteins / genetics

Substances

  • Viral Proteins
  • viral protein 1, rhinovirus