1,3-Alternate 25,27-dibenzoiloxy-26,28-bis-[3-propyloxy]-calix[4]arene-bonded silica gel as a new type of HPLC stationary phase

Magdalena Sliwka-Kaszyńska; Katarzyna Jaszczołt; Aleksander Kołodziejczyk; Janusz Rachoń

doi:10.1016/j.talanta.2005.08.014

1,3-Alternate 25,27-dibenzoiloxy-26,28-bis-[3-propyloxy]-calix[4]arene-bonded silica gel as a new type of HPLC stationary phase

Talanta. 2006 Feb 28;68(5):1560-6. doi: 10.1016/j.talanta.2005.08.014. Epub 2005 Sep 29.

Authors

Magdalena Sliwka-Kaszyńska¹, Katarzyna Jaszczołt, Aleksander Kołodziejczyk, Janusz Rachoń

Affiliation

¹ Department of Organic Chemistry, Gdansk University of Technology, Narutowicza 11/12, 80-952 Gdańsk, Poland.

PMID: 18970499
DOI: 10.1016/j.talanta.2005.08.014

Abstract

A new 1,3-alternate 25,27-dibenzoiloxy-26,28-bis-[3-propyloxy]-calix[4]arene-bonded silica gel stationary phase (1,3-Alt CalixBn) has been prepared and used for the separation of aromatic positional isomers by high-performance liquid chromatography (HPLC). The effect of organic modifier content and pH of the mobile phase on retention and selectivity of these compounds were studied. Application examples were provided for separation of purine and pyrimidine bases and non-steroidal anti-inflammatory drugs.