Surface-enhanced Raman spectrometry for detection in liquid chromatography using a windowless flow cell

Talanta. 1993 Nov;40(11):1741-7. doi: 10.1016/0039-9140(93)80092-6.

Abstract

A windowless flow cell has been developed for surface-enhanced Raman (SER) detection in liquid chromatography. Using colloidal silver as an active substrate, SER spectrometry of banned drugs in sport is presented. The experimental factors of primary influence on the analytical performance of the cell have been studied. The results of SER detection with the proposed cell have been compared to UV detection.