Abstract
REST is a well known repressor of neuronal gene expression. Genome-wide analysis of REST occupancy in different cell types now reveals new and cell-specific roles for REST in embryonic stem cells.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Cell Differentiation / genetics
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Cell Differentiation / physiology
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Embryonic Stem Cells / cytology
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Embryonic Stem Cells / metabolism*
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Gene Expression Regulation, Developmental
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Humans
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Models, Biological
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Neurons / cytology
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Neurons / metabolism
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Repressor Proteins / genetics
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Repressor Proteins / metabolism
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Repressor Proteins / physiology*
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Stem Cells / cytology
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Stem Cells / metabolism*
Substances
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RE1-silencing transcription factor
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Repressor Proteins