Targeting polo-like kinase: learning too little too late?

J Clin Oncol. 2008 Dec 1;26(34):5497-9. doi: 10.1200/JCO.2008.18.6585. Epub 2008 Oct 27.
No abstract available

Publication types

  • Editorial
  • Comment

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology*
  • Biomarkers, Tumor / metabolism
  • Biopsy
  • Cell Cycle Proteins / antagonists & inhibitors*
  • Cell Cycle Proteins / metabolism*
  • Chemistry, Pharmaceutical / methods
  • Drug Design
  • Enzyme Inhibitors / pharmacology
  • Humans
  • Mice
  • Neoplasms / drug therapy*
  • Polo-Like Kinase 1
  • Protein Serine-Threonine Kinases / antagonists & inhibitors*
  • Protein Serine-Threonine Kinases / metabolism*
  • Proto-Oncogene Proteins / antagonists & inhibitors*
  • Proto-Oncogene Proteins / metabolism*
  • Research Design

Substances

  • Antineoplastic Agents
  • Biomarkers, Tumor
  • Cell Cycle Proteins
  • Enzyme Inhibitors
  • Proto-Oncogene Proteins
  • Protein Serine-Threonine Kinases