Yakubovich's oscillatority of circadian oscillations models

Math Biosci. 2008 Dec;216(2):187-91. doi: 10.1016/j.mbs.2008.10.003. Epub 2008 Oct 14.

Abstract

The testing procedure of Yakubovich's oscillatority property is presented. The procedure is applied for two models of circadian oscillations [J.C. Leloup, A. Goldbeter, A model for circadian rhythms in Drosophila incorporating the formation of a complex between the PER and TIM proteins, J. Biol. Rhythms, 13 (1998) 70-87; J.C. Leloup, D. Gonze, A. Goldbeter, Limit cycle models for circadian rhythms based on transcriptional regulation in Drosophila and Neurospora. J. Biol. Rhythms, 14 (1999) 433-448]. Analytical conditions of these models oscillatority are established and bounds on oscillation amplitude are calculated.

MeSH terms

  • Animals
  • Circadian Rhythm / physiology*
  • Drosophila / physiology
  • Models, Biological*
  • Neurospora / physiology