Immune privilege for stem cells: not as simple as it looked

Ann P Chidgey; Richard L Boyd

doi:10.1016/j.stem.2008.09.011

Immune privilege for stem cells: not as simple as it looked

Cell Stem Cell. 2008 Oct 9;3(4):357-8. doi: 10.1016/j.stem.2008.09.011.

Authors

Ann P Chidgey¹, Richard L Boyd

Affiliation

¹ Monash Immunology and Stem Cell Laboratories, Level 3, Building-75, Monash University, Wellington Road, Clayton, Melbourne, Victoria 3800, Australia.

PMID: 18940724
DOI: 10.1016/j.stem.2008.09.011

Abstract

A recent paper in PNAS (Swijnenburg et al., 2008) reveals that human embryonic stem cells are not immune privileged. Potential therapeutic use of these cells will thus depend on the development of new strategies to counter foreign graft rejection by patient immune systems.

Publication types

Introductory Journal Article

MeSH terms

Animals
Cell Differentiation / immunology*
Embryonic Stem Cells / cytology
Embryonic Stem Cells / immunology*
Graft Rejection / immunology
Histocompatibility Antigens / genetics
Histocompatibility Antigens / metabolism*
Humans
Immune Tolerance / immunology*
Immunity, Active
Immunohistochemistry
Luminescent Proteins
Mice
Stem Cell Transplantation
Time Factors
Transplantation Immunology
Transplantation, Homologous

Substances

Histocompatibility Antigens
Luminescent Proteins