Uterine synechiae after bipolar hysteroscopic resection of submucosal myomas in patients with infertility

Fertil Steril. 2009 Nov;92(5):1690-3. doi: 10.1016/j.fertnstert.2008.08.108. Epub 2008 Oct 19.

Abstract

Objective: To determine the rate of uterine synechiae after bipolar hysteroscopic myomectomy in patients suffering from infertility.

Design: Retrospective case series study.

Setting: University obstetrics gynecologic and assisted reproduction center.

Patient(s): A group of 53 patients with primary (n = 30) and secondary (n = 23) infertility.

Intervention(s): Patients underwent bipolar hysteroscopic resection of myomas between 2001 and 2006, and an outpatient hysteroscopy was performed 2 months after the fibroid resection.

Main outcome measure(s): The formation of uterine synechiae and pregnancy rates were collected from the patients' clinical notes.

Result(s): The submucosal myomas were intracavitary class 0 (n = 12), intramural class 1 (n = 19), and intramural class 2 (n = 22). The mean age of the women was 35.0 +/- 4.8 years. The mean myoma size was 25 +/- 11 mm. Postoperative office hysteroscopies revealed synechiae in four (7.5%) of 53 patients. Sixteen (32.7%) of the 49 patients not lost to follow-up conceived, and 12 (24.5%) of them delivered at term. Myoma size >or=3.5 cm and age <35 years were associated with a significantly higher pregnancy rate in univariate and multivariate analysis.

Conclusion(s): The incidence of uterine synechiae after bipolar hysteroscopic resection of fibroids was 7.5%. This appears to be lower than that reported in previous studies using monopolar energy. Bipolar hysteroscopic myomectomy may be a better option for infertile women.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abortion, Spontaneous / epidemiology
  • Abortion, Spontaneous / etiology
  • Adult
  • Age Factors
  • Female
  • Humans
  • Hysteroscopy / adverse effects*
  • Hysteroscopy / methods
  • Infertility, Female / epidemiology*
  • Infertility, Female / etiology
  • Mucous Membrane / pathology
  • Mucous Membrane / surgery
  • Myoma / complications
  • Myoma / surgery*
  • Postoperative Complications / epidemiology
  • Pregnancy
  • Pregnancy Rate
  • Retrospective Studies
  • Tissue Adhesions / complications
  • Tissue Adhesions / epidemiology
  • Tissue Adhesions / etiology
  • Uterine Diseases / complications
  • Uterine Diseases / epidemiology*
  • Uterine Diseases / etiology
  • Uterine Neoplasms / complications
  • Uterine Neoplasms / surgery*