A study was performed to examine the epidemiology of domestic accidents in Sardinia (Italy). A questionnaire was administered to mothers of public school students attending elementary and middle classes during the 2006-2007 school year. Overall 2.075 mothers (59,3% of eligible mothers) participated in the study, 400 (19,3%) of whom declared having had a domestic accident during the previous year. The most frequent lesions were those of the upper (58%) and lower (24%) extremities. Geographical origin and school attended by the student were both found to be statistically associated with domestic accidents.