Synthesis of (+)-DGDP and (-)-7-epialexine

Org Biomol Chem. 2008 Nov 7;6(21):3896-8. doi: 10.1039/b815332a. Epub 2008 Sep 19.

Abstract

The partial reduction of electron deficient pyrroles is an extremely versatile method that allows us to prepare substituted pyrrolidines and pyrrolizidines with trans-diol stereochemistry on the five membered ring.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Pyrroles / chemistry
  • Pyrrolizidine Alkaloids / chemical synthesis*
  • Pyrrolizidine Alkaloids / chemistry
  • Sorbitol / analogs & derivatives*
  • Sorbitol / chemical synthesis
  • Sorbitol / chemistry
  • Stereoisomerism

Substances

  • 2,5-dideoxy-2,5-imino-D-glucitol
  • Pyrroles
  • Pyrrolizidine Alkaloids
  • australine
  • pyrroline
  • Sorbitol