Is early intervention in psychosis effective?

Epidemiol Psichiatr Soc. 2008 Jul-Sep;17(3):227-35. doi: 10.1017/s1121189x00001329.

Abstract

Aims: Psychosis is a traumatic experience for both sufferers and their families. The morbidity and mortality associated with psychosis may be improved by an assertive, specialised, multidisciplinary approach to care, provided at the earliest opportunity. Early Intervention in Psychosis (EIP) uses such approach to improve the individual's short and long-term symptomatic and functional outcome, as well as quality of life. However, there is still controversy about whether this type of intervention is effective enough to justify its associated costs.

Methods: We reviewed evidence from the literature on EIP for schizophrenia spectrum and non-affective psychoses, with particular attention to evidence on its effectiveness in reducing the duration of untreated symptoms, preventing relapses and reducing admission rates, reducing suicide rates, and reducing treatment costs.

Results: There is preliminary evidence that EIP may be effective in delaying transition to psychosis, reducing DUP, preventing relapses, reducing admission and suicidal rates, and reducing treatment costs.

Discussion: EIP remains a stimulating multidisciplinary approach to psychosis and a demanding commitment for mental health professionals and service developers.

Publication types

  • Review

MeSH terms

  • Antipsychotic Agents / economics*
  • Antipsychotic Agents / therapeutic use*
  • Cost-Benefit Analysis
  • Disease Progression
  • Humans
  • Psychotic Disorders / drug therapy*
  • Psychotic Disorders / economics*
  • Time Factors

Substances

  • Antipsychotic Agents