Highly efficient copper-catalyzed amidation of aldehydes by C-H activation

Chemistry. 2008;14(34):10722-6. doi: 10.1002/chem.200801620.

Abstract

We have developed a highly efficient method for the copper-catalyzed amidation of aldehydes in the presence of N-bromosuccinimide (NBS). This method is simple, economical, and has practical advantages for synthesis of imides.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry*
  • Amides / chemistry*
  • Bromosuccinimide / chemistry*
  • Catalysis
  • Copper / chemistry*
  • Imides / chemical synthesis*
  • Imides / chemistry
  • Molecular Structure
  • Stereoisomerism

Substances

  • Aldehydes
  • Amides
  • Imides
  • Copper
  • Bromosuccinimide