Antimicrobial and antiviral activity of hydrolysable tannins

Mini Rev Med Chem. 2008 Oct;8(12):1179-87. doi: 10.2174/138955708786140990.

Abstract

Hydrolysable tannins (HTs), secondary metabolites widely distributed in the plant kingdom, are generally multiple esters of gallic acid with glucose. HTs have been shown to be effective antagonists against viruses, bacteria and eukaryotic microorganisms. The present review examines the antimicrobial and antiviral activity of HTs, the mechanism(s) of action, and some structure-activity relationships.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / pharmacology*
  • Antiviral Agents / chemistry
  • Antiviral Agents / pharmacology*
  • Chemistry, Pharmaceutical / methods
  • Drug Design
  • Drug Evaluation, Preclinical
  • Glucose / chemistry
  • Hydrolysis
  • Hydrolyzable Tannins / chemistry*
  • Inhibitory Concentration 50
  • Models, Chemical
  • Tannins / chemistry*

Substances

  • Anti-Infective Agents
  • Antiviral Agents
  • Hydrolyzable Tannins
  • Tannins
  • Glucose