Sound emission produced by the interaction of several vortices in a two-dimensional homogeneous system obeying the nonlinear Schrödinger (NLS) equation is considered. The radiation effect is explicitly computed in terms of assumed vortex motion. The results are applied to a simple test case of two corotating vortices. The prediction is compared to the result of numerical simulations of the NLS equation. The numerical data give support to the estimate of radiation.