[Studies on flavonoid glycosides of Sarcandra glabra]

Zhongguo Zhong Yao Za Zhi. 2008 Jul;33(14):1700-2.
[Article in Chinese]

Abstract

Objective: To in vestigate the chemical constituents of Sarcandra glabra and obtain a more comprehensive understanding on its effective components.

Method: The constituents were isolated by various column chromatographic method and their structures were elucidated by physico-chemical properties and spectroscopic analysis.

Result: Five flavonoid glycosides were isolated and identified as kaempferol-3-O-beta-D-glucuronide (1), quercetin-3-O-alpha-D-glucuronide (2), quercetin-3-O-beta-D-glucuronopyranoside methyl ester (3), 5, 7, 4'-trihydroxy-8-C-beta-D-glucopyranosyl flavanone (4), neoastilbin (5), 5-O-caffeoylquinic acid methyl ester (6), 3, 4-dihydroxybenzoic acid (7), isofraxidin (8).

Conclusion: Compounds 1-6 were isolated from the genus Sarcandra for the first time. The glucuroide compounds compounds 1-3, were first isolated from the genus Sarcandra.

MeSH terms

  • Caffeic Acids / chemistry
  • Coumarins / chemistry
  • Drugs, Chinese Herbal / chemistry
  • Flavonoids / chemistry*
  • Glucuronides / chemistry
  • Glycosides / chemistry*
  • Magnetic Resonance Spectroscopy
  • Magnoliopsida / chemistry*
  • Spectrometry, Mass, Electrospray Ionization

Substances

  • Caffeic Acids
  • Coumarins
  • Drugs, Chinese Herbal
  • Flavonoids
  • Glucuronides
  • Glycosides
  • isofraxidin