Acute amiodarone-induced pulmonary toxicity: an association of risk factors in a child operated by arterial switch operation

Congenit Heart Dis. 2008 Sep-Oct;3(5):365-7. doi: 10.1111/j.1747-0803.2008.00208.x.

Abstract

Amiodarone is an antiarrhythmic benzoflurane drug with an imposing adverse effect profile. Amiodarone pulmonary toxicity is the major complication. It is well described in adults, whereas it is extremely rare in pediatric patients. This is a case of a child with supraventricular tachycardia post repair of transposition of the great vessels who developed amiodarone toxicity.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Amiodarone / adverse effects*
  • Anti-Arrhythmia Agents / adverse effects*
  • Cardiac Surgical Procedures
  • Drug Hypersensitivity / complications*
  • Drug Hypersensitivity / epidemiology
  • Humans
  • Infant
  • Lung Diseases / chemically induced*
  • Lung Diseases / epidemiology
  • Risk Factors
  • Transposition of Great Vessels / epidemiology
  • Transposition of Great Vessels / surgery*

Substances

  • Anti-Arrhythmia Agents
  • Amiodarone