Development of fluorescent aryltryptophans by Pd mediated cross-coupling of unprotected halotryptophans in water

Chem Commun (Camb). 2008 Oct 21:(39):4831-3. doi: 10.1039/b807512c. Epub 2008 Aug 27.

Abstract

A convenient and high yielding procedure for the Suzuki-Miyaura cross-coupling of unprotected bromo- and chlorotryptophans in water provides fluorescent aryltryptophans.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Fluorescence
  • Molecular Conformation
  • Palladium / chemistry*
  • Spectrometry, Fluorescence / methods
  • Stereoisomerism
  • Tryptophan / analogs & derivatives*
  • Tryptophan / chemical synthesis*
  • Tryptophan / chemistry
  • Water / chemistry*

Substances

  • Water
  • Palladium
  • Tryptophan