Abstract
A highly sensitive microgravimetric lectin biosensor has been developed using carbohydrate-stabilized Au nanoparticles as a signal amplifier; mannose-stabilized Au nanoparticles formed a sandwich-type complex with the target Con A specifically bound to a mannose-modified Au QCM electrode to give an amplified frequency response.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Biosensing Techniques* / instrumentation
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Biosensing Techniques* / methods
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Carbohydrates / chemistry*
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Concanavalin A / analysis*
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Electrodes
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Gold / chemistry*
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Mannose / chemistry
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Metal Nanoparticles / chemistry*
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Particle Size
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Sensitivity and Specificity
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Surface Properties
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Time Factors
Substances
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Carbohydrates
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Concanavalin A
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Gold
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Mannose