Ligand exchanged photoluminescent gold quantum dots functionalized with leading peptides for nuclear targeting and intracellular imaging

Chem Commun (Camb). 2008 Oct 21:(39):4762-4. doi: 10.1039/b808207c. Epub 2008 Aug 8.

Abstract

Ligand exchanged gold quantum dots (GQDs) conjugated with cell-penetrating peptides are a new class of photoluminescent probes for nuclear targeting and intracellular imaging.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Membrane / chemistry
  • Cell Nucleus / chemistry
  • Dendrimers / chemistry
  • Fatty Acids / chemistry*
  • Gold / chemistry*
  • HeLa Cells
  • Humans
  • Ligands
  • Luminescent Agents / chemistry*
  • Luminescent Measurements / methods*
  • Nanostructures / chemistry
  • Nuclear Localization Signals / chemistry*
  • Oligopeptides / chemistry
  • Particle Size
  • Quantum Dots*
  • Simian virus 40 / chemistry
  • Sulfhydryl Compounds / chemistry*
  • Surface Properties

Substances

  • 11-mercaptoundecanoic acid
  • Dendrimers
  • Fatty Acids
  • LTSP protein, synthetic
  • Ligands
  • Luminescent Agents
  • Nuclear Localization Signals
  • Oligopeptides
  • Sulfhydryl Compounds
  • Gold