Abstract
This Highlight covers the synthetic contributions leading to the syntheses of tedanolide and 13-deoxytedanolide or the corresponding macrolactones, respectively. Additionally, the first SAR data for 13-deoxytedanolide (published by Fusetani) are presented.
MeSH terms
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Animals
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Macrolides / chemical synthesis*
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Macrolides / chemistry
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Molecular Structure
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Polyketide Synthases / metabolism
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Porifera / chemistry
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Structure-Activity Relationship
Substances
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13-deoxytedanolide
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Macrolides
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Polyketide Synthases
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tedanolide