[Rotaviruses in younger children in Novosibirsk in 2005-2007: detection and genotyping]

Zh Mikrobiol Epidemiol Immunobiol. 2008 Jul-Aug:(4):12-6.
[Article in Russian]

Abstract

Examination of 1898 patients with acute enteric infection from March 2005 to February 2007 showed that group A rotaviruses were the most frequent cause (35%) of acute gastroenteritis among children under 3 years of age. Majority of cases of rotavirus infection was detected in infants under 1 year of age (71.8%). The peak of sporadic incidence was observed between February and May. High rate of mixed infection (45.6%) was observed - associations of rotaviruses with other viruses (noroviruses, astroviruses) and bacteria (Salmonella, Shigella, enteroinvasive Escherichia coli, Campylobacter, and opportunistic species) were detected. P- and G-genotypes of 337(50.8%) isolates of group A rotaviruses were determined by RT-PCR. The most prevalent strain was P[8]G1 (54.6%) followed by P[8]G3 (10.7%), P[8]G9 (8.6%), P[4]G2 (8.3%), and P[8]G4 (4.5%) genotypes.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Antigens, Viral / genetics
  • Astroviridae Infections / epidemiology
  • Caliciviridae Infections / epidemiology
  • Campylobacter Infections / epidemiology
  • Capsid Proteins / genetics
  • Child, Preschool
  • Comorbidity
  • DNA Primers
  • Diarrhea, Infantile / epidemiology*
  • Diarrhea, Infantile / virology*
  • Enterobacteriaceae Infections / epidemiology
  • Feces / virology
  • Humans
  • Infant
  • Infant, Newborn
  • Rotavirus / classification*
  • Rotavirus / genetics
  • Rotavirus / isolation & purification
  • Rotavirus Infections / epidemiology*
  • Rotavirus Infections / virology*
  • Seasons
  • Siberia / epidemiology
  • Urban Population

Substances

  • Antigens, Viral
  • Capsid Proteins
  • DNA Primers
  • VP4 protein, Rotavirus
  • VP7 protein, Rotavirus