The present study was conducted to study the susceptibility of two different types of Sudanese goats namely: Black Nubian, the Nilotic dwarf goats and ewes of Garag type to experimental infection with Trypanosoma vivax stock isolated from cattle outside tsetse area. The infection caused parasitaemia, anaemia and pyrexia in the infected goats. However, the Nilotic dwarf goats were more tolerant to the infection than the Nubian goats, showing significantly higher values of packed cell volume, haemoglobin concentration, total red and white blood cells counts and significantly low parasitaemia and low body temperature. Garag ewes which were found to be susceptible to T. vivax infection showed different signs of anaemia and pyrexia; it is recommended that comparative studies on sensitivity of this type and other different Sudanese types of sheep to Trypanosomosis should be conducted.