A study in desmotropy

Wolfgang Holzer; Rosa M A Claramunt; Concepción López; Ibon Alkorta; José Elguero

doi:10.1016/j.ssnmr.2007.12.002

A study in desmotropy

Solid State Nucl Magn Reson. 2008 Jul-Sep;34(1-2):68-76. doi: 10.1016/j.ssnmr.2007.12.002. Epub 2008 Aug 3.

Authors

Wolfgang Holzer¹, Rosa M A Claramunt, Concepción López, Ibon Alkorta, José Elguero

Affiliation

¹ Department of Drug and Natural Product Synthesis, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria.

PMID: 18804750
DOI: 10.1016/j.ssnmr.2007.12.002

Abstract

A solid-state NMR/theoretical study of the tautomerism of 4-substituted pyrazolinones was carried out in search of new desmotropes. Thus, the systematic exploration by (13)C and (15)N CPMAS NMR of a series of 4-acylpyrazolin-5-ones has allowed to determine their structure in the solid state and to find a new example of desmotropy that of 1-phenyl-4-acetyl-pyrazolinone.

Publication types

Research Support, Non-U.S. Gov't