The viral aetiology of croup and recurrent croup

Arch Dis Child. 2009 May;94(5):359-60. doi: 10.1136/adc.2008.142984. Epub 2008 Sep 18.

Abstract

Background: Historically croup was subdivided into classic "viral" croup with associated viral upper respiratory tract infections, and recurrent or spasmodic croup where asthma and allergies were thought more important.

Methods: All children admitted to the University Hospital of Wales with croup in 2003 were eligible. Baseline demographics including croup score were recorded and per-nasal swabs taken for virus detection by RT-PCR. Recurrent croup was defined as at least one other admission for croup in the preceding or following 3 years.

Results: Sixty (29.4%) children entered the study, and a viral pathogen was detected in 41 (68%). There was no significant difference in the rate of virus detection between those with single episode croup and recurrent croup.

Conclusions: The aetiologies of viral and recurrent croup appear similar.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Child, Preschool
  • Croup / virology*
  • Diagnosis, Differential
  • Female
  • Humans
  • Male
  • Nasopharynx / virology*
  • Prospective Studies
  • RNA, Viral
  • Recurrence
  • Respiratory Tract Infections / virology
  • Reverse Transcriptase Polymerase Chain Reaction
  • Risk Factors

Substances

  • RNA, Viral