Your diagnosis? A 12-year-old girl with latent tuberculosis presenting with nausea, vomiting and increasing frontal headache

Eur J Pediatr. 2009 Feb;168(2):245-6. doi: 10.1007/s00431-008-0814-y. Epub 2008 Sep 13.

Abstract

A 12-year-old girl with latent Mycobacterium tuberculosis infection and currently receiving prophylaxis with isoniazid presented with nausea, vomiting and increasing frontal headache. Toxicity to the anti-tuberculosis drug was suspected, but her symptoms persisted after isoniazid withdrawal. A computed tomography (CT) scan showed a brain mass to be present.

Publication types

  • Case Reports

MeSH terms

  • Antitubercular Agents / administration & dosage*
  • Antitubercular Agents / adverse effects
  • Cerebellar Neoplasms / diagnosis*
  • Cerebellar Neoplasms / pathology
  • Cerebellar Neoplasms / therapy
  • Child
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Female
  • Headache / etiology*
  • Humans
  • Isoniazid / administration & dosage*
  • Isoniazid / adverse effects
  • Medulloblastoma / diagnosis*
  • Medulloblastoma / pathology
  • Medulloblastoma / therapy
  • Nausea / etiology*
  • Tomography, X-Ray Computed*
  • Tuberculin Test
  • Tuberculosis, Pulmonary / diagnosis*
  • Tuberculosis, Pulmonary / prevention & control
  • Vomiting / etiology*

Substances

  • Antitubercular Agents
  • Isoniazid