Vegetative equilibrium disorders in hypertensive-diseased miners resulted from pathologic developments in the limbic -reticular structures. Those were characterized by a hyperfunction of the ergotropic nerve formations. The vegetative control reorientations were accompanied by narrowing the amplitude of the homeostatic regulation vegetative reactions and engaging the mechanisms of adaptation. The vegetative state stabilization in the diseased workers was attained through a partial avoiding ot the most labour-intensive forms of activity and choosing more preferable labour operations. But the latter did not entirely exclude the labour conditions which would result into inadequate vegetative reactions.