Objective: To study the clinical effect of treating parotid gland malignant tumor with facial never-preserving surgery combined with 125I seed implant brachytherapy.
Methods: Thirty-two patients with parotid gland malignancy underwent tumor and parotid gland excision while preserving facial never. According to treating plan system (TPS), 125I seeds were implanted into the target area during or after operation. The patients were followed up after operation and the local tumor control and facial nerve function were observed.
Results: Tumor recurrence was not found in any patient treated after 12 to 44 months of follow up. All patients did not show obvious radiation-related complications. The facial never function of all patients was basically normal 6 months after operation.
Conclusions: For parotid gland malignant tumor, surgery combined with 125I seeds implant brachytherapy can save facial nerve function, and the short-term effects were satisfactory.