Synthesis of simple adenosine diphosphate ribose analogues

Olivier P Chevallier; Marie E Migaud

doi:10.1080/15257770802341350

Synthesis of simple adenosine diphosphate ribose analogues

Nucleosides Nucleotides Nucleic Acids. 2008 Oct;27(10):1127-43. doi: 10.1080/15257770802341350.

Authors

Olivier P Chevallier¹, Marie E Migaud

Affiliation

¹ School of Chemistry and Chemical Engineering, Queen's University, Belfast, Northern Ireland, United Kingdom.

PMID: 18788043
DOI: 10.1080/15257770802341350

Abstract

[See figures]. The synthesis of analogues of adenosine diphosphate ribose and acetylated adenosine diphosphate ribose, modified at the northern pentose, is reported. The stereochemistry at the acetylated centers was chosen to minimize acetyl migration and dictated the overall synthetic strategy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acetylation
Adenosine Diphosphate Ribose / analogs & derivatives*
Adenosine Diphosphate Ribose / chemical synthesis*
Molecular Structure

Substances

Adenosine Diphosphate Ribose