OGG1, MYH and MTH1 gene variants identified in gastric cancer patients exhibiting both 8-hydroxy-2'-deoxyguanosine accumulation and low inflammatory cell infiltration in their gastric mucosa

J Genet. 2008 Aug;87(2):181-6. doi: 10.1007/s12041-008-0028-0.

Authors

Masanori Goto¹, Kazuya Shinmura, Hidetaka Yamada, Toshihiro Tsuneyoshi, Haruhiko Sugimura

Affiliation

¹ First Department of Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, Shizuoka 431-3192, Japan.

PMID: 18776649
DOI: 10.1007/s12041-008-0028-0

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

8-Hydroxy-2'-Deoxyguanosine
Aged
Cell Movement
DNA Glycosylases / genetics*
DNA Repair Enzymes / genetics*
Deoxyguanosine / analogs & derivatives*
Deoxyguanosine / metabolism
Female
Gastric Mucosa / enzymology
Gastric Mucosa / pathology*
Humans
Inflammation
Male
Mutation / genetics*
Phosphoric Monoester Hydrolases / genetics*
Polymorphism, Single Nucleotide / genetics
Stomach Neoplasms / enzymology
Stomach Neoplasms / genetics*

Substances

8-Hydroxy-2'-Deoxyguanosine
Phosphoric Monoester Hydrolases
DNA Glycosylases
mutY adenine glycosylase
oxoguanine glycosylase 1, human
8-oxodGTPase
DNA Repair Enzymes
Deoxyguanosine