Abstract
Synthesis of novel cyclopropyl pyrimidine and purine nucleoside derivatives was successfully achieved using one pot reactions including an alkylation, an oxirane-ring opening reaction and a lactonization and a hydroboration-oxidation as the key steps in order to find new antiherpetic agent.
MeSH terms
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Adenine / analogs & derivatives*
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Adenine / chemical synthesis
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Adenine / chemistry
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Antiviral Agents / chemical synthesis*
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Antiviral Agents / chemistry
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Herpesviridae / drug effects
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Thymine / analogs & derivatives*
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Thymine / chemical synthesis
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Thymine / chemistry
Substances
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Antiviral Agents
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Adenine
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Thymine