Metachromatic leukodystrophy: magnetic resonance imaging (diffusion weighted image--DWI)

Neuro Endocrinol Lett. 2008 Aug;29(4):428-30.

Abstract

Ten years old patient with juvenile form of metachromatic leukodystrophy (MDL) is presented. Apart from standard magnetic resonance (MR) protocol, the diffusion weighted sequence was performed and apparent diffusion coefficient (ADC) map was constructed. The cause of restricted diffusion is considered to be the deposits of metachromatic substance in the intercellular space, apparently similar reason for decrease of speed of diffusion in other storage diseases.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Diffusion Magnetic Resonance Imaging*
  • Humans
  • Leukodystrophy, Metachromatic / diagnosis
  • Leukodystrophy, Metachromatic / pathology*