Scandium-catalyzed carbon-carbon bond-forming reactions of 3-sulfanyl- and 3-selanylpropargyl alcohols

Mitsuhiro Yoshimatsu; Tokutaro Otani; Saki Matsuda; Teruhisa Yamamoto; Arisa Sawa

doi:10.1021/ol801533p

Scandium-catalyzed carbon-carbon bond-forming reactions of 3-sulfanyl- and 3-selanylpropargyl alcohols

Org Lett. 2008 Oct 2;10(19):4251-4. doi: 10.1021/ol801533p. Epub 2008 Sep 3.

Authors

Mitsuhiro Yoshimatsu¹, Tokutaro Otani, Saki Matsuda, Teruhisa Yamamoto, Arisa Sawa

Affiliation

¹ Department of Chemistry, Faculty of Education, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan. yoshimae@gifu-u.ac.jp

PMID: 18763783
DOI: 10.1021/ol801533p

Abstract

The scandium-catalyzed substitution reactions of the phenylsulfanyl and phenylselanyl propargyl alcohols 3a- i and 7a- h regioselectively proceeded to give the propargylated compounds 4 and 8 in high yields.