Antimitotic drug injections and radiotherapy: a review of the effectiveness of treatment for hypertrophic scars and keloids

Int J Low Extrem Wounds. 2008 Sep;7(3):151-9. doi: 10.1177/1534734608322099.

Abstract

Scars are a common complication of surgery or burn wound management. Scars occur over the body, affecting people of both sexes and all ages. Scar therapy is a constant clinical challenge; antimitotic drugs and radiotherapy are used with varying degrees of success. This article examines the success of both these types of treatment modalities.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Antibiotics, Antineoplastic / therapeutic use
  • Antimetabolites, Antineoplastic / therapeutic use
  • Antimitotic Agents / administration & dosage
  • Antimitotic Agents / therapeutic use*
  • Cicatrix, Hypertrophic / drug therapy*
  • Cicatrix, Hypertrophic / radiotherapy*
  • Colchicine / therapeutic use
  • Fluorouracil / therapeutic use
  • Humans
  • Keloid / drug therapy*
  • Keloid / radiotherapy*
  • Keratolytic Agents / therapeutic use
  • Mitomycin / therapeutic use
  • Radiotherapy / methods
  • Tretinoin / therapeutic use
  • Tubulin Modulators / therapeutic use

Substances

  • Adrenal Cortex Hormones
  • Antibiotics, Antineoplastic
  • Antimetabolites, Antineoplastic
  • Antimitotic Agents
  • Keratolytic Agents
  • Tubulin Modulators
  • Mitomycin
  • Tretinoin
  • Colchicine
  • Fluorouracil