Acaricidal activity of limonene, limonene oxide and beta-amino alcohol derivatives on Rhipicephalus (Boophilus) microplus

Stela Regina Ferrarini; Mônica Oliveira Duarte; Ricardo G da Rosa; Verônica Rolim; Vera Lucia Eifler-Lima; Gilsane von Poser; Vera Lucia Sardá Ribeiro

doi:10.1016/j.vetpar.2008.07.006

Acaricidal activity of limonene, limonene oxide and beta-amino alcohol derivatives on Rhipicephalus (Boophilus) microplus

Vet Parasitol. 2008 Oct 20;157(1-2):149-53. doi: 10.1016/j.vetpar.2008.07.006. Epub 2008 Jul 19.

Authors

Stela Regina Ferrarini¹, Mônica Oliveira Duarte, Ricardo G da Rosa, Verônica Rolim, Vera Lucia Eifler-Lima, Gilsane von Poser, Vera Lucia Sardá Ribeiro

Affiliation

¹ Programa de Pós Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, 90610-000 Porto Alegre, RS, Brazil.

PMID: 18755549
DOI: 10.1016/j.vetpar.2008.07.006

Abstract

Limonene, limonene oxide and eight beta-amino alcohol derivatives obtained by synthesis were investigated for the effect on egg hatchability and mortality rates of newly hatched larvae of the cattle tick Rhipicephalus (Boophilus) microplus. At the doses between 10 microg/ml and 2.5 microg/ml all the compounds were highly lethal to the larvae and some of them showed activity at lower concentrations. The effect on the eggs hatchability was observed in all the treatments.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Alcohols / chemical synthesis
Amino Alcohols / toxicity*
Animals
Cyclohexane Monoterpenes
Cyclohexenes / toxicity*
Insecticides / toxicity*
Larva / drug effects
Limonene
Molecular Structure
Monoterpenes / toxicity*
Ovum / drug effects
Rhipicephalus / drug effects*
Structure-Activity Relationship
Terpenes / toxicity*

Substances

Amino Alcohols
Cyclohexane Monoterpenes
Cyclohexenes
Insecticides
Monoterpenes
Terpenes
limonene-1,2-epoxide
Limonene