Abstract
We describe the management and clinical outcome of pregnancies among 100 Greek Cypriot women with thalassaemia: 88 with thalassaemia major and 12 with thalassaemia intermedia. A total of 152 successful pregnancies and 161 deliveries were included. All patients had endocrine assessment and frequent ferritin measurements. Multiple successful pregnancies included 7 twins and 1 triple pregnancy. Pregnant thalassaemics required significantly larger amount of total blood transfusion during pregnancy. There was a statistically significant increase in the ferritin levels during pregnancy, and levels remained significantly higher after pregnancy. Most pregnancies resulted in delivery of full-term healthy babies, and obstetric complications were rare, although some problems were encountered.
MeSH terms
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Aftercare
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Blood Transfusion / statistics & numerical data*
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Delivery, Obstetric / methods
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Delivery, Obstetric / statistics & numerical data
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Female
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Ferritins / blood
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Genetic Counseling
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Greece / epidemiology
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Health Services Needs and Demand
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Humans
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Monitoring, Physiologic
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Postnatal Care / organization & administration*
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Practice Guidelines as Topic
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Pregnancy
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Pregnancy Complications, Hematologic / blood
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Pregnancy Complications, Hematologic / diagnosis
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Pregnancy Complications, Hematologic / epidemiology
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Pregnancy Complications, Hematologic / therapy*
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Pregnancy Outcome / epidemiology*
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Prenatal Care / organization & administration*
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Retrospective Studies
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Statistics, Nonparametric
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Thalassemia / blood
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Thalassemia / diagnosis
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Thalassemia / epidemiology
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Thalassemia / therapy*