Spontaneous retropharyngeal hematoma is a rare but potentially fatal disease. It occurs with no underlying medical condition such as trauma, hemorrhagic diathesis, or medically induced anticoagulation.We report a case of a 48-year-old man who presented with progressive dysphagia, signs of inflammation, and a reduced general health status. There was distinct hemorrhagic swelling of the posterior and lateral walls of the nasopharynx, oropharynx, and hypopharynx, as well as red discoloration of the neck. No underlying medical conditions, medications, or trauma were reported.In light of the current case and the available literature, we present the necessary diagnostic procedures and treatment options. Because the course of this disease might be fatal due to rapid airway obstruction and progressive internal blood loss, it is of utmost importance to keep this diagnosis in mind for differential diagnostic considerations.