Self-reported adherence to treatment and quality of life in mild to moderate acne

Dermatology. 2008;217(4):309-14. doi: 10.1159/000151441. Epub 2008 Aug 20.

Abstract

Background: Adherence to treatment is a mayor issue in dermatology, and its relationship to quality of life has barely been studied.

Objective: To evaluate the relationship between scores on the Skindex-29 skin disease assessment scale and adherence to treatment in patients with acne.

Methods: An observational, prospective study of 1,628 patients carried out by 252 clinicians in Spain.

Results: Adherence was related to better objective and subjective severity index scores and better Skindex-29 scale scores at the end of the study. Young, male and unemployed patients had the worst adherence scores. Baseline and final Skindex-29 scale scores were significantly worse in non-adherent females, while non-adherent males scored better. Reasons for non-adherence were side effects for older patients and forgetfulness for younger ones.

Conclusion: Dermatologists should explain that adherence to treatment is linked to better outcomes and better quality of life. Young females with high Skindex-29 scale scores and males with low Skindex scores are especially prone to non-adherence.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acne Vulgaris / drug therapy*
  • Administration, Cutaneous
  • Administration, Oral
  • Adult
  • Anti-Bacterial Agents / therapeutic use*
  • Drug Therapy, Combination
  • Erythromycin / therapeutic use*
  • Female
  • Humans
  • Male
  • Ointments / therapeutic use
  • Patient Compliance*
  • Prospective Studies
  • Quality of Life
  • Severity of Illness Index
  • Sickness Impact Profile
  • Spain
  • Surveys and Questionnaires
  • Treatment Outcome
  • Zinc / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Ointments
  • Erythromycin
  • Zinc