Abstract
A 19-year-old Japanese woman with a 4-year history of Crohn's disease (CD) developed high fever, polyarthralgia, and painful subcutaneous nodules of the legs. A skin biopsy showed panarteritis with fibrinoid necrosis in the deep dermis. Endoscopic examination showed aphthous lesions in the entire colon. She was diagnosed with cutaneous polyarteritis nodosa (PAN) associated with CD. Steroid therapy improved her symptoms. To our knowledge, this is the first Japanese case of cutaneous PAN associated with CD.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
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Crohn Disease / complications
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Crohn Disease / drug therapy
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Crohn Disease / pathology*
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Drug Therapy, Combination
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Female
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Glucocorticoids / therapeutic use
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Humans
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Mesalamine / therapeutic use
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Necrosis / complications
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Necrosis / pathology
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Polyarteritis Nodosa / complications
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Polyarteritis Nodosa / drug therapy
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Polyarteritis Nodosa / pathology*
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Prednisolone / therapeutic use
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Skin / blood supply
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Skin / pathology*
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Skin Diseases / drug therapy
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Skin Diseases / etiology
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Skin Diseases / pathology*
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Treatment Outcome
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Young Adult
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Glucocorticoids
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Mesalamine
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Prednisolone