Review of a current role of mass spectrometry for proteome research

Anal Chim Acta. 2008 Aug 22;624(1):16-36. doi: 10.1016/j.aca.2008.06.017. Epub 2008 Jun 22.

Abstract

This review is intended to give readers a snapshot of current mass spectrometry for proteomics research. It covers a brief history of mass spectrometry proteomic research, peptidomics and proteomics for biomarker search, quantitative proteomics, proteomics with post-translational modification and future perspective of proteomics.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biomarkers / analysis
  • Humans
  • Mass Spectrometry*
  • Peptides / analysis
  • Protein Conformation
  • Protein Processing, Post-Translational
  • Proteins / analysis*
  • Proteomics / methods*

Substances

  • Biomarkers
  • Peptides
  • Proteins