The presence of fatty substances: neutral lipids, triglycerides, and phospholipids was detected in the adrenal cortex 30 days after the termination of detergent influence on white laboratory rats. We found that neutral lipids were of increased quantity in the glomerular, fascicular and reticular zone. Triglycerides were present in a greater extent in the entire cortex of animals which were subjected to the influence of detergents. Phospholipids offer an analogue picture: their quantity was increased in all parts of the adrenal cortex in the experimental animals. The described features of the adrenal cortex after detergent influence termination, considering the three groups of fatty substances, undoubtedly indicate the increased activity of the adrenal cortex.