Concomitant coronary artery disease among Asian ischaemic stroke patients

Ann Acad Med Singap. 2008 Jul;37(7):573-5.

Abstract

Introduction: Coronary artery disease (CAD) is the leading cause of death following ischaemic stroke. We aimed to study the prevalence and associations of concomitant CAD among ischaemic stroke patients in Singapore.

Materials and methods: We prospectively studied 2686 consecutive Asian ischaemic stroke patients.

Results: CAD was prevalent among 24% of the study patients. Older age, hypertension, diabetes, hyperlipidaemia, atrial fibrillation, large stroke and South Asian ethnicity were independently associated with CAD.

Conclusions: The variables found to be associated with CAD are known atherosclerotic risk factors (older age, hypertension, diabetes, hyperlipidaemia) or associations of cardioembolic stroke (atrial fibrillation, large stroke). The over-representation of South Asians with concomitant CAD is consistent with the high burden of CAD in this ethnic group.

MeSH terms

  • Aged
  • Brain Ischemia / complications*
  • Brain Ischemia / epidemiology
  • Coronary Artery Disease / complications*
  • Coronary Artery Disease / epidemiology
  • Female
  • Humans
  • Male
  • Prevalence
  • Prospective Studies
  • Regression Analysis
  • Risk Factors
  • Singapore / epidemiology
  • Stroke / complications*
  • Stroke / epidemiology
  • Survival Rate
  • Time Factors