A finite element (FE) model of human body head (HBM-head) was developed in accordance with human head anatomy. The model consists of scalp, skull, dura mater, cerebro-spinal fluid (CSF), pia mater, cerebrum, cerebellum, ventricle, brain stem, falx, tentorium, etc. The cadaveric head impact tests were conducted to validate the head FE model. The kinematic and kinetic responses as well as the intracranial pressure distribution of the head model were compared with experimental data. It is proved that the head FE model has good biofidelity and can be used to study head-brain injuries and injury mechanisms in vehicle traffic accidents.