Ossifying fibromyxoid tumor invading the spine: a case report and review of the literature

Skeletal Radiol. 2008 Dec;37(12):1137-40. doi: 10.1007/s00256-008-0562-0. Epub 2008 Aug 7.

Abstract

Ossifying fibromyxoid tumors were first described in 1989. They are composed of small round cells dispersed in a myxoid matrix and contain bone, osteoid, and collagen. Bone invasion is very rare. Our case was unusual because of the spinal location of the tumor and its invasive features including destruction of the cortex of the vertebral body, and invasion of the spinal canal causing a radioculopathy. The clinical presentation, radiologic features, and histopathologic findings are described, and the relevant literature is reviewed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Female
  • Fibroma, Ossifying / diagnosis*
  • Fibroma, Ossifying / radiotherapy
  • Fibroma, Ossifying / surgery
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Magnetic Resonance Imaging / methods
  • Neoplasm Invasiveness
  • Ossification, Heterotopic / diagnosis*
  • Ossification, Heterotopic / radiotherapy
  • Ossification, Heterotopic / surgery
  • Rare Diseases
  • Soft Tissue Neoplasms / diagnosis*
  • Soft Tissue Neoplasms / radiotherapy
  • Soft Tissue Neoplasms / surgery
  • Spinal Canal / diagnostic imaging
  • Spinal Neoplasms / diagnosis*
  • Spinal Neoplasms / surgery
  • Tomography, X-Ray Computed / methods