[Influence repeated stress on immune responciveness and monooxigenase activity of normotensive and hypertensive rats]

V E Tseĭlikman; D A Kozochkin; A L Markel'; O B Tseĭlikman; S V Sibiriak; A I Sinitskiĭ; D A Sysakov; A S Simbitrsev

[Influence repeated stress on immune responciveness and monooxigenase activity of normotensive and hypertensive rats]

Ross Fiziol Zh Im I M Sechenova. 2008 May;94(5):574-80.

[Article in Russian]

Authors

V E Tseĭlikman, D A Kozochkin, A L Markel', O B Tseĭlikman, S V Sibiriak, A I Sinitskiĭ, D A Sysakov, A S Simbitrsev

PMID: 18669362

Abstract

Repeated stress led to antipodal directions in immune system and cytochrome P450 activities of normotensive and hypertensive rats. Enhancement of the Reaction of Delayed Hypersensitivity, suppression of cytochrome P450-mediated monooxigenase activities were observed in Wistar rats. On the contrary, in the NISAG decrease of the Reaction Delayed Hypersensitivity, elevation of cytochrome P450-mediated monooxigenase activities were observed, as comparison with Wistar rats.

Publication types

English Abstract
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Aryl Hydrocarbon Hydroxylases / immunology
Aryl Hydrocarbon Hydroxylases / metabolism
Cytochrome P-450 CYP1A1 / immunology
Cytochrome P-450 CYP1A1 / metabolism
Cytochrome P-450 CYP2B1 / immunology
Cytochrome P-450 CYP2B1 / metabolism
Hypersensitivity, Delayed / enzymology
Hypersensitivity, Delayed / immunology*
Hypertension / enzymology
Hypertension / immunology*
Mixed Function Oxygenases / immunology*
Mixed Function Oxygenases / metabolism
Rats
Rats, Wistar
Steroid Hydroxylases / immunology
Steroid Hydroxylases / metabolism
Stress, Physiological / enzymology
Stress, Physiological / immunology*

Substances

Mixed Function Oxygenases
Steroid Hydroxylases
Aryl Hydrocarbon Hydroxylases
Cytochrome P-450 CYP1A1
Cytochrome P-450 CYP2B1
steroid 16-beta-hydroxylase