Nutritional therapy for active Crohn's disease

World J Gastroenterol. 2008 Jul 21;14(27):4420-3. doi: 10.3748/wjg.14.4420.

Abstract

Nutritional therapy for active Crohn's disease (CD) is an underutilised form of treatment in adult patients, though its use is common in the paediatric population. There is evidence that nutritional therapy can effectively induce remission of CD in adult patients. Enteral nutrition therapy is safe and generally well tolerated. Meta-analysis data suggest that corticosteroids are superior to nutritional treatment for induction of remission in active CD. However, the potential side effects of such pharmacotherapy must be taken into consideration. This review examines the evidence for the efficacy of elemental and polymeric diets, and the use of total parenteral nutrition in active CD.

Publication types

  • Letter
  • Review

MeSH terms

  • Adrenal Cortex Hormones / pharmacology*
  • Clinical Trials as Topic
  • Crohn Disease / diet therapy*
  • Crohn Disease / therapy
  • Humans
  • Nutrition Therapy*
  • Nutritional Sciences
  • Remission Induction
  • Steroids / therapeutic use
  • Treatment Outcome

Substances

  • Adrenal Cortex Hormones
  • Steroids