[Progress in the study of heterogeneous nuclear ribonucleoprotein and its relation with diseases]

Sheng Li Ke Xue Jin Zhan. 2008 Apr;39(2):109-13.
[Article in Chinese]

Abstract

Heterogeneous nuclear ribonucleoprotein ( hnRNPs) is a widely expressing protein family in human body,which has a close relationship with health. HnRNPs takes part in the developing processes of many diseases such as viral diseases, tumor, autoimmune system diseases and so on. hnRNPs also regulates the expression of special genes such as cyp2a5, CYP2A6, eNOS. There are numerous proteins in vivo and hnRNPs links with them in numerous ways. Much work is needed to unclose the relationship between hnRNPs and related diseases or gene regulation.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Autoimmune Diseases / physiopathology
  • Gene Expression Regulation / physiology*
  • Heterogeneous-Nuclear Ribonucleoprotein Group A-B / physiology
  • Heterogeneous-Nuclear Ribonucleoprotein Group C / physiology
  • Heterogeneous-Nuclear Ribonucleoproteins / physiology*
  • Humans
  • Neoplasms / physiopathology
  • RNA-Binding Proteins / genetics
  • RNA-Binding Proteins / metabolism
  • Virus Diseases / physiopathology

Substances

  • Heterogeneous-Nuclear Ribonucleoprotein Group A-B
  • Heterogeneous-Nuclear Ribonucleoprotein Group C
  • Heterogeneous-Nuclear Ribonucleoproteins
  • RNA-Binding Proteins