[Study on effect of demethoxycurcumin in Curcuma long on stability of curcumin]

Zhong Yao Cai. 2008 Apr;31(4):592-4.
[Article in Chinese]

Abstract

Objective: To investigate effect of demethoxycurcumin on stability of curcumin.

Methods: To add the demethoxycurcumin to pure curcumin, the change of curcumin was determined by HPLC and the dynamics of curcumin degradation was investigated.

Result: The stability both obtained from alcohol and demethoxycurcumin improved the stabilization of curcumin, the demi-period of curcumin prolonged with the addition of demethoxycurcumin.

Conclusion: The commixture of curcumin and demethoxycurcumin are more stable than pure curcumin at the same conditions. Stability of curcumin is improved by demethoxycurcumin,it is crude stabilizing agent.

MeSH terms

  • Chromatography, High Pressure Liquid
  • Curcuma / chemistry*
  • Curcumin / analogs & derivatives*
  • Curcumin / chemistry*
  • Curcumin / isolation & purification*
  • Curcumin / metabolism
  • Diarylheptanoids
  • Drug Stability
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification
  • Ethanol / chemistry
  • Hydrogen-Ion Concentration
  • Plants, Medicinal / chemistry
  • Rhizome / chemistry
  • Technology, Pharmaceutical / methods

Substances

  • Diarylheptanoids
  • Drugs, Chinese Herbal
  • Ethanol
  • Curcumin
  • demethoxycurcumin