Abstract
Thermosensitive drug delivery can be used as substances carriers, which are applied in oral system, vaginal systems of release, applied on skin, the rectal, nasal, passed to eyes and parenteral. Sol-gel transition of the prepared formulations at physiological temperature ranges of the body makes possible their application in the liquid state and subsequent gelification in situ providing a prolonged release of the active substance at the application site.
MeSH terms
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Administration, Cutaneous
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Biopolymers / chemistry
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Chemistry, Pharmaceutical
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Delayed-Action Preparations
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Drug Administration Routes
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Drug Carriers / chemistry*
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Drug Carriers / classification*
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Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry
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Ophthalmic Solutions / administration & dosage
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Phase Transition
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Polymers / chemistry*
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Polymers / classification*
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Spironolactone / chemistry
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Structure-Activity Relationship
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Temperature
Substances
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Biopolymers
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Delayed-Action Preparations
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Drug Carriers
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Ophthalmic Solutions
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Polymers
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Hydrogel, Polyethylene Glycol Dimethacrylate
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Spironolactone