Biological and pathobiological functions of gelatinase dimers and complexes

Nabin Malla; Stian Sjøli; Jan-Olof Winberg; Elin Hadler-Olsen; Lars Uhlin-Hansen

doi:10.1080/03008200802151755

Biological and pathobiological functions of gelatinase dimers and complexes

Connect Tissue Res. 2008;49(3):180-4. doi: 10.1080/03008200802151755.

Authors

Nabin Malla¹, Stian Sjøli, Jan-Olof Winberg, Elin Hadler-Olsen, Lars Uhlin-Hansen

Affiliation

¹ Department of Medical Biochemistry, Institute of Medical Biology, Medical Faculty, University of Tromsø, Tromsø, Norway.

PMID: 18661338
DOI: 10.1080/03008200802151755

Abstract

The two matrix metalloproteinases, MMP-2 and MMP-9, are known to form various dimer complexes. In the present review, some of these complexes are described along with their biological and pathobiological functions.

Publication types

Review

MeSH terms

Animals
Dimerization
Extracellular Matrix / metabolism*
Glycosaminoglycans / metabolism*
Haptoglobins / metabolism
Humans
Lipocalins / metabolism
Matrix Metalloproteinase 2 / chemistry
Matrix Metalloproteinase 2 / metabolism*
Matrix Metalloproteinase 9 / chemistry
Matrix Metalloproteinase 9 / metabolism*
Proteoglycans / metabolism*
Tissue Inhibitor of Metalloproteinases / metabolism*
alpha-Fetoproteins / metabolism

Substances

Glycosaminoglycans
Haptoglobins
Lipocalins
Proteoglycans
Tissue Inhibitor of Metalloproteinases
alpha-Fetoproteins
Matrix Metalloproteinase 2
Matrix Metalloproteinase 9